


These tools, especially if enabled with telemedicine, will not only help assess a patient’s health status, triage the patient to appropriate care, determine potential diagnoses, and predict recovery, but also, it will help provide real-time medical monitoring, for instance, people in home-quarantine. In return, the demand for an accurate home-diagnostic tool for blood pressure measurements, along with other vital signs (e.g., temperature, respiratory rate) has increased massively. Not only this provides essential data to enhance the materials’ properties and optimize their performance, but also, it highlights new perspectives and provides suggestions to develop the next generation pressure sensors for clinical use.Ĭardiovascular diseases caused 31% of deaths worldwide, and recently, they had the highest confirmed death cases in Italy and China during the novel pandemic known as the coronavirus disease 2019 (COVID-19). Then, we carefully reviewed various categories of functional materials utilized in sensor building blocks allowing for comparative analysis of the performance of a wide range of materials throughout the sensor operational-life cycle.

In our unique transdisciplinary approach, we studied the fundamentals of blood pressure and examined its measuring modalities while focusing on their clinical use and sensing principles to identify material functionalities. Here, we present an extensive review and critical analysis of various materials applied in the design and fabrication of wearable sensors. One of the key obstacles in the further development of wearable sensors for medical applications is the lack of comprehensive technical evaluation of sensor materials against the expected clinical performance. While the progress in this area is tremendously impressive, few wearable sensors with the capability of real-time blood pressure monitoring are approved for clinical use. Advancements in materials science and fabrication techniques have contributed to the significant growing attention to a wide variety of sensors for digital healthcare.
